Some pharmacies will operate evening vaccine clinics to help the roll-out to children aged between 12 and 15.
Registration on the HSE portal will open tomorrow for the age group, with first jabs to be given out as soon as this weekend.
Parents' permission is required for children to get a vaccine, so its hoped the evening clinics will ease the burden on work pressures.
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Darragh O'Loughlin from the Irish Pharmacy Union says they are ready to roll-out the vaccines.