Robbie Henshaw has been ruled out of Ireland's test against South Africa tomorrow.
Leinster player Henshaw was absent from training on Friday morning due to a hamstring issue. Ulster's Stuart McCloskey comes into the team and will wear the number 12 shirt.
Jimmy O'Brien will take McCloskey's place on the bench.
Ireland: Hugo Keenan; Robert Baloucoune, Garry Ringrose, Stuart McCloskey, Mack Hansen; Johnny Sexton (capt), Conor Murray; Andrew Porter, Dan Sheehan, Tadhg Furlong; Tadhg Beirne, James Ryan; Peter O'Mahony, Josh van der Flier, Caelan Doris
Replacements: Rob Herring, Cian Healy, Finlay Bealham, Kieran Treadwell, Jack Conan, Jamison Gibson Park, Joey Carbery, Jimmy O'Brien