Caelan Doris captains Leinster for the first time in Europe as Leinster take on Leicester in the Investec Champions Cup.
Jamison Gibson-Park and Jack Conan are both set to make their 50th appearance in the Champions Cup Round of 16 tie in Aviva Stadium.
The starting line-up sees three changes from the team that defeated Leicester in January. Hugo Keenan returns to start at full-back, with Jordan Larmour and James Lowe named on the wing.
Robbie Henshaw and Jamie Osborne form the centre partnership once more, with Ross Byrne and Gibson-Park linking up at half-back.
In the pack, Andrew Porter, Dan Sheehan and Tadhg Furlong join forces for the first time since the Guinness Six Nations, in the front row.
Ross Molony and Joe McCarthy are in the heart of the pack, with Ryan Baird, Josh van der Flier and Doris in the back-row.
Among the replacements, Conan is joined by Academy scrum-half Ben Murphy and the returning Ciarán Frawley.
Leinster: 15. Hugo Keenan, 14. Jordan Larmour, 13. Robbie Henshaw, 12. Jamie Osborne, 11. James Lowe, 10. Ross Byrne, 9. Jamison Gibson-Park, 1. Andrew Porter, 2. Dan Sheehan, 3. Tadhg Furlong, 4. Ross Molony, 5. Joe McCarthy, 6. Ryan Baird, 7. Josh van der Flier, 8. Caelan Doris (C).
Replacements: 16. Rónan Kelleher, 17. Cian Healy, 18. Michael Ala’alatoa, 19. Jason Jenkins, 20. Jack Conan, 21. Ben Murphy, 22. Harry Byrne, 23. Ciarán Frawley.
Leinster v Leicester Tigers
Investec Champions Cup Round of 16
Saturday April 6
Aviva Stadium, Kick-off: 8pm
Referee: Pierre Brousset (FFR)